Information on Limb-Girdle Muscular Dystrophy
Posted by Goody on 10/9/08 in Uncategorized
All limb-girdle muscular dystrophies (LGMD) show a similar distribution of muscle weakness, affecting both upper arms and legs.
Limb-girdle muscular dystrophy is known hereditarily heterogeneous. LGMD2A is caused by mutations on chromosome 15 in the calpain-3 gene. There are at least 19 forms of LGMD, and they’re classified by the inherited flaws that show to cause them. Limb-girdle muscular dystrophy can begin in childhood, adolescence, young adulthood or even later. Both genders are affected equally. When limb-girdle muscular dystrophy begins in childhood. It’s not yet possible to predict the course of LGMD in an individual.
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